Issue 84, 2015

A single nanoparticle-based sensor for hydrogen peroxide (H2O2) via cytochrome c-mediated plasmon resonance energy transfer

Abstract

Herein, we report a novel method for H2O2 detection based on a single plasmonic nanoprobe via cytochrome c (Cyt c)-mediated plasmon resonance energy transfer (PRET). Dynamic spectral changes were observed in the fingerprint quenching dip of a single plasmonic nanoprobe in response to changes in the redox state of Cyt c, induced by H2O2. Based on the changes in the spectral profile of the single plasmonic nanoprobe, H2O2 was successfully detected in a wide concentration range from 100 mM to 10 nM, including physiologically relevant micromolar and nanomolar concentrations.

Graphical abstract: A single nanoparticle-based sensor for hydrogen peroxide (H2O2) via cytochrome c-mediated plasmon resonance energy transfer

Supplementary files

Article information

Article type
Communication
Submitted
29 Jun 2015
Accepted
21 Aug 2015
First published
21 Aug 2015

Chem. Commun., 2015,51, 15370-15373

A single nanoparticle-based sensor for hydrogen peroxide (H2O2) via cytochrome c-mediated plasmon resonance energy transfer

Y. Kim, J. Y. Park, H. Y. Kim, M. Lee, J. Yi and I. Choi, Chem. Commun., 2015, 51, 15370 DOI: 10.1039/C5CC05327G

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