Jump to main content
Jump to site search
PLANNED MAINTENANCE Close the message box

Scheduled maintenance work on Wednesday 27th March 2019 from 11:00 AM to 1:00 PM (GMT).

During this time our website performance may be temporarily affected. We apologise for any inconvenience this might cause and thank you for your patience.

Issue 66, 2015
Previous Article Next Article

Diastereoselective Johnson–Corey–Chaykovsky trifluoroethylidenation

Author affiliations


(2,2,2-Trifluoroethyl)diphenylsulfonium triflate was found to be an efficient ylide reagent for the Johnson–Corey–Chaykovsky reaction to afford trifluoromethyl epoxides, cyclopropanes and aziridines. Interestingly, excellent but different diastereoselectivity was observed for these transformations. Both trifluoromethyl epoxides and cyclopropanes were obtained with trans-selectivity, whereas aziridines were obtained with cis-selectivity.

Graphical abstract: Diastereoselective Johnson–Corey–Chaykovsky trifluoroethylidenation

Back to tab navigation

Supplementary files

Publication details

The article was received on 17 Jun 2015, accepted on 06 Jul 2015 and first published on 06 Jul 2015

Article type: Communication
DOI: 10.1039/C5CC04991A
Citation: Chem. Commun., 2015,51, 13127-13130

  •   Request permissions

    Diastereoselective Johnson–Corey–Chaykovsky trifluoroethylidenation

    Y. Duan, B. Zhou, J. Lin and J. Xiao, Chem. Commun., 2015, 51, 13127
    DOI: 10.1039/C5CC04991A

Search articles by author