Issue 61, 2015

Copper-catalyzed cascade azidation–cyclization of tryptophols and tryptamines

Abstract

The copper-catalyzed cascade azidation–cyclization of tryptophols and tryptamines has been developed. This cascade reaction uses readily available and cheap sodium azide as a nitrogen source to gave 3-azido furoindolines and pyrrolidinoindolines under mild reaction conditions.

Graphical abstract: Copper-catalyzed cascade azidation–cyclization of tryptophols and tryptamines

Supplementary files

Article information

Article type
Communication
Submitted
13 May 2015
Accepted
26 Jun 2015
First published
26 Jun 2015

Chem. Commun., 2015,51, 12293-12296

Copper-catalyzed cascade azidation–cyclization of tryptophols and tryptamines

P. Zhang, W. Sun, G. Li, L. Hong and R. Wang, Chem. Commun., 2015, 51, 12293 DOI: 10.1039/C5CC03964A

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