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Issue 52, 2015
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A highly selective and fast-response fluorescent probe for visualization of enzymatic H2S production in vitro and in living cells

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Abstract

An o-fluorinated-azido-capped rhodamine probe can react with H2S efficiently and selectively to give large off–on fluorescence enhancement. The probe was used to develop an assay for cystathionine β-synthase acitivity and for in situ visualization of endogenously produced H2S in living cells.

Graphical abstract: A highly selective and fast-response fluorescent probe for visualization of enzymatic H2S production in vitro and in living cells

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Publication details

The article was received on 04 May 2015, accepted on 19 May 2015 and first published on 19 May 2015


Article type: Communication
DOI: 10.1039/C5CC03707G
Chem. Commun., 2015,51, 10463-10466

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    A highly selective and fast-response fluorescent probe for visualization of enzymatic H2S production in vitro and in living cells

    L. Wei, Z. Zhu, Y. Li, L. Yi and Z. Xi, Chem. Commun., 2015, 51, 10463
    DOI: 10.1039/C5CC03707G

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