Issue 87, 2015
From the journal:

Chemical Communications

Unimolecular micelles of amphiphilic cyclodextrin-core star-like block copolymers for anticancer drug delivery†

Zhigang Xu,a   Shiying Liu,a   Hui Liu,a   Cangjie Yang,a   Yuejun Kanga  and  Mingfeng Wang*a  

* Corresponding authors

a School of Chemical and Biomedical Engineering, Nanyang Technological University, 62 Nanyang Drive, Singapore 637459, Singapore
E-mail: mfwang@ntu.edu.sg
Fax: +65 6316 8746
Tel: +65 6794 7553

Abstract

Well-defined star-like amphiphilic polymers composed of a β-cyclodextrin core, from which 21 hydrophobic poly(lactic acid) arms and hydrophilic poly(ethylene glycol) arms are grafted sequentially, form robust and uniform unimolecular micelles that are biocompatible and efficient in the delivery of anticancer drugs.

Graphical abstract: Unimolecular micelles of amphiphilic cyclodextrin-core star-like block copolymers for anticancer drug delivery

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Article information

DOI
https://doi.org/10.1039/C5CC02743H
Article type
Communication
Submitted
02 Apr 2015
Accepted
01 Jun 2015
First published
29 Jun 2015

Chem. Commun., 2015,51, 15768-15771

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Unimolecular micelles of amphiphilic cyclodextrin-core star-like block copolymers for anticancer drug delivery

Z. Xu, S. Liu, H. Liu, C. Yang, Y. Kang and M. Wang, Chem. Commun., 2015, 51, 15768 DOI: 10.1039/C5CC02743H

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