Issue 54, 2015

Photoinduced cytotoxicity of a photochromic diarylethene via caspase cascade activation

Abstract

The photo-generated closed-ring isomer of bis(5-methyl-2-phenylthiazoyl)perfluorocyclopentene shows cytotoxicity to Madin–Darby canine kidney (MDCK) cells through a caspase cascade and induces apoptosis of cells.

Graphical abstract: Photoinduced cytotoxicity of a photochromic diarylethene via caspase cascade activation

Supplementary files

Article information

Article type
Communication
Submitted
16 Mar 2015
Accepted
29 May 2015
First published
29 May 2015

Chem. Commun., 2015,51, 10957-10960

Author version available

Photoinduced cytotoxicity of a photochromic diarylethene via caspase cascade activation

J. Okuda, Y. Tanaka, R. Kodama, K. Sumaru, K. Morishita, T. Kanamori, S. Yamazoe, K. Hyodo, S. Yamazaki, T. Miyatake, S. Yokojima, S. Nakamura and K. Uchida, Chem. Commun., 2015, 51, 10957 DOI: 10.1039/C5CC02200B

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