Issue 41, 2015

Mononuclear nonheme iron(iii) complexes that show superoxide dismutase-like activity and antioxidant effects against menadione-mediated oxidative stress

Abstract

This communication describes the superoxide dismutase (SOD)-like activity of mononuclear iron(III) complexes with pentadentate monocarboxylamido ligands. The SOD activity can be controlled by the electronic nature of the substituent group on the ligand. The nitro-substituted complex showed clear cytoprotective activity against menadione-mediated oxidative stress in cultured cells.

Graphical abstract: Mononuclear nonheme iron(iii) complexes that show superoxide dismutase-like activity and antioxidant effects against menadione-mediated oxidative stress

Supplementary files

Article information

Article type
Communication
Submitted
10 Mar 2015
Accepted
20 Apr 2015
First published
20 Apr 2015

Chem. Commun., 2015,51, 8702-8704

Author version available

Mononuclear nonheme iron(III) complexes that show superoxide dismutase-like activity and antioxidant effects against menadione-mediated oxidative stress

Y. Hitomi, Y. Iwamoto, A. Kashida and M. Kodera, Chem. Commun., 2015, 51, 8702 DOI: 10.1039/C5CC02019K

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