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Issue 47, 2015
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Elucidating the relationship between superoxide anion levels and lifespan using an enhanced two-photon fluorescence imaging probe

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Abstract

We report a new reversible fluorescent two-photon (TP) probe (PY-CA) with high TP absorption cross section and pH-independent fluorescence response, which allow monitoring of O2˙ fluxes dynamically, selectively and sensitively. The imaging results indicate that O2˙ at high levels can shorten the life of Caenorhabditis elegans.

Graphical abstract: Elucidating the relationship between superoxide anion levels and lifespan using an enhanced two-photon fluorescence imaging probe

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Publication details

The article was received on 25 Feb 2015, accepted on 27 Apr 2015 and first published on 06 May 2015


Article type: Communication
DOI: 10.1039/C5CC01670C
Citation: Chem. Commun., 2015,51, 9710-9713
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    Elucidating the relationship between superoxide anion levels and lifespan using an enhanced two-photon fluorescence imaging probe

    W. Zhang, X. Wang, P. Li, F. Huang, H. Wang, W. Zhang and B. Tang, Chem. Commun., 2015, 51, 9710
    DOI: 10.1039/C5CC01670C

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