Exploiting anthracene photodimerization within peptides: light induced sequence-selective DNA binding

Abstract

The unprecedented use of anthracene photodimerization within a protein or peptide system is explored through its incorporation into a DNA-binding peptide, derived from the GCN4 transcription factor. This study demonstrates an effective and dynamic interplay between a photoreaction and a peptide–DNA assembly, with each process able to exert control over the other.