Dynamic combinatorial chemistry on a monolayer protected gold nanoparticle

Abstract

Here, we show that the addition of Hg²⁺ or Ag⁺ metal ions to a dynamic system composed of monolayer protected gold nanoparticles (Au NPs) and a mixture of four nucleotides (dGMP, dAMP, TMP, and dCMP) leads to the self-selection of TMP or dGMP, respectively, on the monolayer surface.