Issue 21, 2015

A multiple gadolinium complex decorated fullerene as a highly sensitive T1 contrast agent

Abstract

We report a simple strategy to construct a multiple gadolinium complex decorated fullerene (CGDn) as an enhanced T1 contrast agent. The CGDn exhibits much higher T1 relaxivity (∼49.7 mM−1 s−1) than individual Gd-DOTA, and shows excellent T1 contrast enhancement ability both in vitro and in vivo.

Graphical abstract: A multiple gadolinium complex decorated fullerene as a highly sensitive T1 contrast agent

Supplementary files

Article information

Article type
Communication
Submitted
12 Jan 2015
Accepted
03 Feb 2015
First published
03 Feb 2015

Chem. Commun., 2015,51, 4390-4393

A multiple gadolinium complex decorated fullerene as a highly sensitive T1 contrast agent

L. Wang, X. Zhu, X. Tang, C. Wu, Z. Zhou, C. Sun, S. Deng, H. Ai and J. Gao, Chem. Commun., 2015, 51, 4390 DOI: 10.1039/C5CC00285K

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