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Issue 22, 2015
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An antibody-graphene oxide nanoribbon conjugate as a surface enhanced laser desorption/ionization probe with high sensitivity and selectivity

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Abstract

Graphene oxide nanoribbons (GONRs) were covalently functionalized with an antibody using polyethylene glycol (PEG) as a linker to produce a novel probe for surface enhanced laser desorption/ionization mass spectrometry (SELDI MS). This probe provides a highly sensitive and selective platform for enrichment and MS detection of small molecules in complex media.

Graphical abstract: An antibody-graphene oxide nanoribbon conjugate as a surface enhanced laser desorption/ionization probe with high sensitivity and selectivity

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Article information


Submitted
30 Dec 2014
Accepted
10 Feb 2015
First published
10 Feb 2015

Chem. Commun., 2015,51, 4619-4622
Article type
Communication

An antibody-graphene oxide nanoribbon conjugate as a surface enhanced laser desorption/ionization probe with high sensitivity and selectivity

J. Wang, M. Cheng, Z. Zhang, L. Guo, Q. Liu and G. Jiang, Chem. Commun., 2015, 51, 4619
DOI: 10.1039/C4CC10401C

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