Indium-catalyzed, novel route to β,β-disubstituted indanones via tandem Nakamura addition–hydroarylation–decarboxylation sequence

Abstract

A novel method for the construction of β,β-disubstituted indanones has been developed via tandem Nakamura addition–hydroarylation–decarboxylation process. Indium(III) triflate was demonstrated as a versatile multitasking catalyst, which catalyzes three different chemical transformations under one-pot conditions.