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Issue 6, 2015
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A transition-metal-free, one-pot procedure for the synthesis of α,β-epoxy ketones by oxidative coupling of alkenes and aldehydes via base catalysis

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Abstract

A new strategy for the synthesis of epoxides is presented. This process allows the direct synthesis of epoxides from alkenes and aldehydes through C–H functionalization and C–C/C–O bond formation.

Graphical abstract: A transition-metal-free, one-pot procedure for the synthesis of α,β-epoxy ketones by oxidative coupling of alkenes and aldehydes via base catalysis

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Article information


Submitted
20 Nov 2014
Accepted
27 Nov 2014
First published
27 Nov 2014

Chem. Commun., 2015,51, 1012-1015
Article type
Communication
Author version available

A transition-metal-free, one-pot procedure for the synthesis of α,β-epoxy ketones by oxidative coupling of alkenes and aldehydes via base catalysis

Q. Ke, B. Zhang, B. Hu, Y. Jin and G. Lu, Chem. Commun., 2015, 51, 1012
DOI: 10.1039/C4CC09260K

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