Issue 10, 2015
From the journal:

Chemical Communications

The facile surface chemical modification of a single glass nanopore and its use in the nonenzymatic detection of uric acid†

Haili He,ab   Xiaolong Xu,a   Ping Wang,a   Lizhen Chenab  and  Yongdong Jin*a  

* Corresponding authors

a State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, Jilin, P. R. China
E-mail: ydjin@ciac.ac.cn

b University of Chinese Academy of Sciences, Beijing 100049, P. R. China

Abstract

A conical glass nanopore was first modified with ultrathin gold nanofilm via a simple and innovative chemical reduction of HAuCl4 on a surface-attached poly(L-histidine) monolayer in the presence of a mild reductant, NH2OH·HCl, followed by surface functionalization with 2-thiouracil, and exploited for the selective nonenzymatic detection of uric acid and especially for serum sample detection.

Graphical abstract: The facile surface chemical modification of a single glass nanopore and its use in the nonenzymatic detection of uric acid

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Article information

DOI
https://doi.org/10.1039/C4CC09185J
Article type
Communication
Submitted
18 Nov 2014
Accepted
09 Dec 2014
First published
11 Dec 2014

Chem. Commun., 2015,51, 1914-1917

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The facile surface chemical modification of a single glass nanopore and its use in the nonenzymatic detection of uric acid

H. He, X. Xu, P. Wang, L. Chen and Y. Jin, Chem. Commun., 2015, 51, 1914 DOI: 10.1039/C4CC09185J

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