Issue 2, 2015
From the journal:

Chemical Communications

Smart pH-responsive upconversion nanoparticles for enhanced tumor cellular internalization and near-infrared light-triggered photodynamic therapy†

Sheng Wang,a   Lei Zhang,b   Chunhong Dong,a   Lin Su,a   Hanjie Wang*a  and  Jin Chang*a  

* Corresponding authors

a Institute of Nanobiotechnology, School of Life Sciences, School of Materials Science and Engineering, Tianjin University and Tianjin Key Laboratory of Composites and Functional Materials, Tianjin, PR China
E-mail: jinchang@tju.edu.cn, wanghj@tju.edu.cn

b School of Environmental Science and Engineering, Tianjin University, Tianjin 300072, PR China

Abstract

A smart pH-responsive photodynamic therapy system based on upconversion nanoparticle loaded PEG coated polymeric lipid vesicles (RB-UPPLVs) was designed and prepared. These RB-UPPLVs which are promising agents for deep cancer photodynamic therapy applications can achieve enhanced tumor cellular internalization and near-infrared light-triggered photodynamic therapy.

Graphical abstract: Smart pH-responsive upconversion nanoparticles for enhanced tumor cellular internalization and near-infrared light-triggered photodynamic therapy

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Article information

DOI
https://doi.org/10.1039/C4CC08178A
Article type
Communication
Submitted
15 Oct 2014
Accepted
10 Nov 2014
First published
10 Nov 2014

Chem. Commun., 2015,51, 406-408

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Smart pH-responsive upconversion nanoparticles for enhanced tumor cellular internalization and near-infrared light-triggered photodynamic therapy

S. Wang, L. Zhang, C. Dong, L. Su, H. Wang and J. Chang, Chem. Commun., 2015, 51, 406 DOI: 10.1039/C4CC08178A

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