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Issue 8, 2015
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A fast-responsive mitochondria-targeted fluorescent probe detecting endogenous hypochlorite in living RAW 264.7 cells and nude mouse

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Abstract

A very fast-responsive fluorescent probe PZ–Py for imaging mitochondrial HClO/ClO, with a relatively long emission wavelength, was prepared. The limit of detection was evaluated to be 17.9 nM. Moreover, the probe PZ–Py was successfully applied in the imaging of endogenous HClO/ClO in the mitochondria of RAW 264.7 cells and living nude mouse.

Graphical abstract: A fast-responsive mitochondria-targeted fluorescent probe detecting endogenous hypochlorite in living RAW 264.7 cells and nude mouse

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Article information


Submitted
19 Sep 2014
Accepted
20 Nov 2014
First published
02 Dec 2014

Chem. Commun., 2015,51, 1442-1445
Article type
Communication
Author version available

A fast-responsive mitochondria-targeted fluorescent probe detecting endogenous hypochlorite in living RAW 264.7 cells and nude mouse

H. Xiao, K. Xin, H. Dou, G. Yin, Y. Quan and R. Wang, Chem. Commun., 2015, 51, 1442
DOI: 10.1039/C4CC07411D

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