Quick re-introduction of selective scalar interactions in a pure-shift NMR spectrum

Abstract

A new 1D NMR experiment cited as ‘Quick G-SERF’, which re-introduces selective proton–proton scalar interactions in a pure shift spectrum during real time data acquisition, is reported. The method provides information on multiple proton–proton couplings from a single experiment, analogous to the 2D G-SERF technique, while significantly shortening the experimental time by 1–2 orders of magnitude due to reduced dimension and enhanced sensitivity.