Issue 93, 2014
From the journal:

Chemical Communications

Chemically-induced redox switching of a metalloprotein reveals thermodynamic and kinetic heterogeneity, one molecule at a time†

Namik Akkilic,*a   Fenna van der Grient,a   Muhammad Kamrana  and  Nusrat J. M. Sanghamitraa  

* Corresponding authors

a Biological and Soft Matter Physics, LION, Leiden University, Niels Bohrweg 2, 2333 CA Leiden, The Netherlands
E-mail: namikakkilic@gmail.com

Abstract

Oxidation (off state) and reduction (on state) of a single azurin molecule is monitored, one electron at a time, which depend on the chemical redox potential. By analysing the fluorescence time traces from individual azurin molecules, reaction kinetics and redox thermodynamics were determined.

Graphical abstract: Chemically-induced redox switching of a metalloprotein reveals thermodynamic and kinetic heterogeneity, one molecule at a time

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C4CC06334A
Article type
Communication
Submitted
12 Aug 2014
Accepted
01 Oct 2014
First published
02 Oct 2014

Chem. Commun., 2014,50, 14523-14526

Author version available

Download author version (PDF)

Permissions

Request permissions

Chemically-induced redox switching of a metalloprotein reveals thermodynamic and kinetic heterogeneity, one molecule at a time

N. Akkilic, F. van der Grient, M. Kamran and N. J. M. Sanghamitra, Chem. Commun., 2014, 50, 14523 DOI: 10.1039/C4CC06334A

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements