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Issue 88, 2014
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A domino desulfurative coupling–acylation–hydration–Michael addition process for the synthesis of polysubstituted tetrahydro-4H-pyrido[1,2-a]pyrimidines

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Abstract

A novel method for the synthesis of the polysubstituted tetrahydro-4H-pyrido[1,2-a]pyrimidines through a domino desulfurative coupling–acylation–hydration and Michael addition sequence was established.

Graphical abstract: A domino desulfurative coupling–acylation–hydration–Michael addition process for the synthesis of polysubstituted tetrahydro-4H-pyrido[1,2-a]pyrimidines

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Publication details

The article was received on 03 Jul 2014, accepted on 03 Sep 2014 and first published on 05 Sep 2014


Article type: Communication
DOI: 10.1039/C4CC05090H
Citation: Chem. Commun., 2014,50, 13555-13558

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    A domino desulfurative coupling–acylation–hydration–Michael addition process for the synthesis of polysubstituted tetrahydro-4H-pyrido[1,2-a]pyrimidines

    Z. Yan, Z. Quan, Y. Da, Z. Zhang and X. Wang, Chem. Commun., 2014, 50, 13555
    DOI: 10.1039/C4CC05090H

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