Issue 83, 2014

Recent advances in the catalytic asymmetric 1,3-dipolar cycloaddition of azomethine ylides

Abstract

Catalytic asymmetric 1,3-dipolar cycloadditions of azomethine ylides have turned out to be one of the most efficient methods for the preparation of enantioenriched pyrrolidines. The past decade has witnessed the development of a bunch of well-defined catalytic systems capable of affording excellent diastereo and enantioselectivities. Recently, a great effort has been focused on expanding the scope of the cycloaddition with regard to both reaction partners. In this review, we will discuss important advances that have been reported in this area since 2011.

Graphical abstract: Recent advances in the catalytic asymmetric 1,3-dipolar cycloaddition of azomethine ylides

Article information

Article type
Feature Article
Submitted
09 Jun 2014
Accepted
11 Jul 2014
First published
11 Jul 2014

Chem. Commun., 2014,50, 12434-12446

Author version available

Recent advances in the catalytic asymmetric 1,3-dipolar cycloaddition of azomethine ylides

J. Adrio and J. C. Carretero, Chem. Commun., 2014, 50, 12434 DOI: 10.1039/C4CC04381B

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