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Issue 83, 2014
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Recent advances in the catalytic asymmetric 1,3-dipolar cycloaddition of azomethine ylides

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Abstract

Catalytic asymmetric 1,3-dipolar cycloadditions of azomethine ylides have turned out to be one of the most efficient methods for the preparation of enantioenriched pyrrolidines. The past decade has witnessed the development of a bunch of well-defined catalytic systems capable of affording excellent diastereo and enantioselectivities. Recently, a great effort has been focused on expanding the scope of the cycloaddition with regard to both reaction partners. In this review, we will discuss important advances that have been reported in this area since 2011.

Graphical abstract: Recent advances in the catalytic asymmetric 1,3-dipolar cycloaddition of azomethine ylides

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Publication details

The article was received on 09 Jun 2014, accepted on 11 Jul 2014 and first published on 11 Jul 2014


Article type: Feature Article
DOI: 10.1039/C4CC04381B
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Citation: Chem. Commun., 2014,50, 12434-12446

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    Recent advances in the catalytic asymmetric 1,3-dipolar cycloaddition of azomethine ylides

    J. Adrio and J. C. Carretero, Chem. Commun., 2014, 50, 12434
    DOI: 10.1039/C4CC04381B

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