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Issue 67, 2014
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Detection of cancer cells using triplex DNA molecular beacons based on expression of enhanced green fluorescent protein (eGFP)

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Abstract

A novel strategy was proposed for Ramos cell detection by combining the expression of enhanced green fluorescent protein (eGFP) with the cell aptamer recognition and the triplex molecular beacons. This system was successfully applied to cancer cell detection with high sensitivity and specificity.

Graphical abstract: Detection of cancer cells using triplex DNA molecular beacons based on expression of enhanced green fluorescent protein (eGFP)

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Publication details

The article was received on 22 May 2014, accepted on 01 Jul 2014 and first published on 04 Jul 2014


Article type: Communication
DOI: 10.1039/C4CC03925D
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Chem. Commun., 2014,50, 9547-9549

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    Detection of cancer cells using triplex DNA molecular beacons based on expression of enhanced green fluorescent protein (eGFP)

    D. Xi, X. Wang, S. Ai and S. Zhang, Chem. Commun., 2014, 50, 9547
    DOI: 10.1039/C4CC03925D

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