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Issue 56, 2014
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A prospective antibacterial for drug-resistant pathogens: a dual warhead amphiphile designed to track interactions and kill pathogenic bacteria by membrane damage and cellular DNA cleavage

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Abstract

A rationally designed bactericidal amphiphile acts on compelling targets and has the potential to disarm resistance development in pathogenic bacteria.

Graphical abstract: A prospective antibacterial for drug-resistant pathogens: a dual warhead amphiphile designed to track interactions and kill pathogenic bacteria by membrane damage and cellular DNA cleavage

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Article information


Submitted
30 Mar 2014
Accepted
16 May 2014
First published
16 May 2014

Chem. Commun., 2014,50, 7434-7436
Article type
Communication

A prospective antibacterial for drug-resistant pathogens: a dual warhead amphiphile designed to track interactions and kill pathogenic bacteria by membrane damage and cellular DNA cleavage

D. Thiyagarajan, S. Goswami, C. Kar, G. Das and A. Ramesh, Chem. Commun., 2014, 50, 7434
DOI: 10.1039/C4CC02354D

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