Visible light induced fast synthesis of protein–polymer conjugates: controllable polymerization and protein activity

Abstract

Herein visible light is used to induce RAFT polymerization from protein for preparing protein–polymer conjugates at ambient temperature. Polymerization is fast and can be conveniently controlled with irradiation time. By site-specific polymerization of NIPAm to protein, the protein activity is maintained and in certain cases it presents an efficient on–off-switchable property.