Palladium-catalyzed R2(O)P directed C(sp2)–H acetoxylation†
Abstract
A novel and efficient Pd-catalyzed C–H acetoxylation is described. The approach uses R2(O)P as a directing group to synthesize various substituted 2′-phosphorylbiphenyl-2-OAc compounds. Notably, the reaction exhibits smooth operation under mild conditions and shows good functional group tolerance. Products are obtained with high selectivity and yields.