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Issue 27, 2014
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A facile mechanophore functionalization of an amphiphilic block copolymer towards remote ultrasound and redox dual stimulus responsiveness

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Abstract

Two different site-specific cleavage mechanisms for copolymer micelles under ultrasound and redox were confirmed. The finding that ultrasound induced mechanochemical cleavage of central ester bonds can open up a new way in the design of novel ultrasound responsive copolymer micelles for drug release.

Graphical abstract: A facile mechanophore functionalization of an amphiphilic block copolymer towards remote ultrasound and redox dual stimulus responsiveness

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Supplementary files

Article information


Submitted
06 Jan 2014
Accepted
10 Feb 2014
First published
11 Feb 2014

Chem. Commun., 2014,50, 3575-3578
Article type
Communication

A facile mechanophore functionalization of an amphiphilic block copolymer towards remote ultrasound and redox dual stimulus responsiveness

R. Tong, X. Lu and H. Xia, Chem. Commun., 2014, 50, 3575
DOI: 10.1039/C4CC00103F

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