Enantioselective, intermolecular [2+2] photocycloaddition reactions of 3-acetoxyquinolone: total synthesis of (−)-pinolinone†
Abstract
The natural product (−)-pinolinone was synthesised via a concise route (six steps, 17% overall yield) from 3-acetoxyquinolone, employing an enantioselective intermolecular [2+2] photocycloaddition as the key step.