Structural landscape of the 1 : 1 benzoic acid : isonicotinamide cocrystal†
Abstract
The acid–pyridine heterosynthon may be used as a “molecular” module to probe the structural landscape of the benzoic acid : isonicotinamide 1 : 1 cocrystal, BA : INA. Experimental structures of 1 : 1 cocrystals of fluorobenzoic acids (FBA) with isonicotinamide (INA) contain this heterosynthon and correspond to high-energy structures of 1 : 1 BA : INA.