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Issue 8, 2014
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DNA strand-displacement-induced fluorescence enhancement for highly sensitive and selective assay of multiple microRNA in cancer cells

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Abstract

We report a new strategy for evaluating multiple miRNA expressions in cancer cells based on DNA strand-displacement-induced fluorescence enhancement. This assay has the ability to discriminate the target from even single-base mismatched sequences or other miRNAs.

Graphical abstract: DNA strand-displacement-induced fluorescence enhancement for highly sensitive and selective assay of multiple microRNA in cancer cells

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Supplementary files

Article information


Submitted
05 Sep 2013
Accepted
18 Nov 2013
First published
19 Nov 2013

Chem. Commun., 2014,50, 1012-1014
Article type
Communication

DNA strand-displacement-induced fluorescence enhancement for highly sensitive and selective assay of multiple microRNA in cancer cells

P. Wu, Y. Tu, Y. Qian, H. Zhang and C. Cai, Chem. Commun., 2014, 50, 1012
DOI: 10.1039/C3CC46773B

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