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Issue 97, 2013
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In vitro and in vivo imaging application of a 1,8-naphthalimide-derived Zn2+ fluorescent sensor with nuclear envelope penetrability

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Abstract

A newly developed fluorescent sensor, Naph-BPEA, shows a specific turn-on response to Zn2+ and can be excited by visible light. The in situ nuclear Zn2+ imaging in HeLa and HepG2 cells reveals the nuclear envelope penetrability of the sensor. The specific sensor location in a zebrafish larva was also demonstrated.

Graphical abstract: In vitro and in vivo imaging application of a 1,8-naphthalimide-derived Zn2+ fluorescent sensor with nuclear envelope penetrability

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Article information


Submitted
07 Sep 2013
Accepted
14 Oct 2013
First published
15 Oct 2013

Chem. Commun., 2013,49, 11430-11432
Article type
Communication

In vitro and in vivo imaging application of a 1,8-naphthalimide-derived Zn2+ fluorescent sensor with nuclear envelope penetrability

C. Zhang, Z. Liu, Y. Li, W. He, X. Gao and Z. Guo, Chem. Commun., 2013, 49, 11430
DOI: 10.1039/C3CC46862C

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