Issue 88, 2013

Fluorescent and radiolabeled triphenylphosphonium probes for imaging mitochondria

Abstract

Triphenylphosphonium-fluorochromes (TPP-fluorochromes) are a new class of spectrally variable, mitochondrially targeted probes, with an [18F] labeling option which, when enabled, allows imaging of a cardiac perfusion deficit using PET/CT.

Graphical abstract: Fluorescent and radiolabeled triphenylphosphonium probes for imaging mitochondria

Supplementary files

Article information

Article type
Communication
Submitted
30 Jul 2013
Accepted
10 Sep 2013
First published
27 Sep 2013

Chem. Commun., 2013,49, 10361-10363

Fluorescent and radiolabeled triphenylphosphonium probes for imaging mitochondria

H. Yuan, H. Cho, H. H. Chen, M. Panagia, D. E. Sosnovik and L. Josephson, Chem. Commun., 2013, 49, 10361 DOI: 10.1039/C3CC45802D

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