Jump to main content
Jump to site search

Issue 82, 2013
Previous Article Next Article

An ultrasensitive homogeneous chemiluminescent assay for microRNAs

Author affiliations

Abstract

On the basis of a dual-amplification strategy, microRNA (miRNA) hybridization amplification by a duplex-specific nuclease (DSN) and signal amplification by a DNAzyme, a highly sensitive and selective homogeneous miRNA assay is developed. By leveraging on the cumulative and selective nature of the DSN amplification process, excellent sensitivity and selectivity are accomplished.

Graphical abstract: An ultrasensitive homogeneous chemiluminescent assay for microRNAs

Back to tab navigation

Publication details

The article was received on 27 Jun 2013, accepted on 13 Aug 2013 and first published on 09 Sep 2013


Article type: Communication
DOI: 10.1039/C3CC44824J
Chem. Commun., 2013,49, 9401-9403

  •   Request permissions

    An ultrasensitive homogeneous chemiluminescent assay for microRNAs

    H. Deng, Y. Ren, W. Shen and Z. Gao, Chem. Commun., 2013, 49, 9401
    DOI: 10.1039/C3CC44824J

Search articles by author

Spotlight

Advertisements