Issue 83, 2013

Design of electrochemical detection of thiols based on the cleavage of the disulfide bond coupled with thionine modified gold nanoparticle-assisted amplification

Abstract

A new strategy for the electrochemical detection of thiols based on the disulfide cleavage combined with gold nanoparticle (AuNP) assisted signal amplification and an AuNP and graphene (GR) and ionic liquid (IL) modified carbon paste electrode (AuNP/GR/CILE). A superior detection limit of 0.4 pM toward glutathione could be achieved.

Graphical abstract: Design of electrochemical detection of thiols based on the cleavage of the disulfide bond coupled with thionine modified gold nanoparticle-assisted amplification

Supplementary files

Article information

Article type
Communication
Submitted
15 Jun 2013
Accepted
20 Aug 2013
First published
20 Aug 2013

Chem. Commun., 2013,49, 9603-9605

Design of electrochemical detection of thiols based on the cleavage of the disulfide bond coupled with thionine modified gold nanoparticle-assisted amplification

X. Hun, W. Sun, H. Zhu, F. Du, F. Liu, Y. Xu and Y. He, Chem. Commun., 2013, 49, 9603 DOI: 10.1039/C3CC44487B

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