Issue 75, 2013
From the journal:

Chemical Communications

Selective fluorescent-free detection of biomolecules on nanobiochips by wavelength dependent-enhanced dark field illumination†

Seungah Lee,a   Hyunung Yub  and  Seong Ho Kang*a  

* Corresponding authors

a Department of Applied Chemistry, Kyung Hee University, Yongin-si, Gyeonggi-do 446-701, Republic of Korea
E-mail: shkang@khu.ac.kr
Fax: +82 31 201 2340
Tel: +82 31 201 3349

b Nanobio Fusion Research Center, Korea Research Institute of Standards and Science, Daejeon 305-600, Republic of Korea

Abstract

Individual silver nanoparticle-conjugated target protein (cTnI) molecules on gold-nanopatterned chip were selectively detected by wavelength dependent-enhanced dark field illumination. Using specific nanoparticles with unique sizes and materials, the immunotargeted nanoparticle on the chips was detected at the single-molecule level by monitoring changes in the plasmonic resonance based on wavelength dependence.

Graphical abstract: Selective fluorescent-free detection of biomolecules on nanobiochips by wavelength dependent-enhanced dark field illumination

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Article information

DOI
https://doi.org/10.1039/C3CC44153A
Article type
Communication
Submitted
03 Jun 2013
Accepted
18 Jul 2013
First published
18 Jul 2013

Chem. Commun., 2013,49, 8335-8337

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Selective fluorescent-free detection of biomolecules on nanobiochips by wavelength dependent-enhanced dark field illumination

S. Lee, H. Yu and S. H. Kang, Chem. Commun., 2013, 49, 8335 DOI: 10.1039/C3CC44153A

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