Issue 48, 2013

Highly sensitive fluorescent detection of small molecules, ions, and proteins using a universal label-free aptasensor

Abstract

A facile and universal aptamer-based label-free approach for highly selective and sensitive fluorescence detection of a broad range of targets including small molecules, inorganic ions and proteins was developed by using PicoGreen to transduce the fluorescent signal of the double stranded DNA duplex formed between a free aptamer and its complementary strand.

Graphical abstract: Highly sensitive fluorescent detection of small molecules, ions, and proteins using a universal label-free aptasensor

Supplementary files

Article information

Article type
Communication
Submitted
16 Apr 2013
Accepted
24 Apr 2013
First published
25 Apr 2013

Chem. Commun., 2013,49, 5465-5467

Highly sensitive fluorescent detection of small molecules, ions, and proteins using a universal label-free aptasensor

Z. Lv, J. Liu, Y. Zhou, Z. Guan, S. Yang, C. Li and A. Chen, Chem. Commun., 2013, 49, 5465 DOI: 10.1039/C3CC42801J

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