Jump to main content
Jump to site search

Issue 49, 2013
Previous Article Next Article

A ratiometric naphthalimide sensor for live cell imaging of copper(i)

Author affiliations

Abstract

A new naphthalimide derivative bearing a tetrathia-azacrown for high affinity and selective binding to Cu+ was synthesised. Copper recognition properties in solution were evaluated using 1H NMR and fluorescence spectroscopy. Live cell imaging by confocal microscopy highlighted the capabilities of the new sensor for the two-wavelength detection of intracellular monovalent copper in neuronal cells.

Graphical abstract: A ratiometric naphthalimide sensor for live cell imaging of copper(i)

Back to tab navigation

Supplementary files

Publication details

The article was received on 21 Mar 2013, accepted on 23 Apr 2013 and first published on 25 Apr 2013


Article type: Communication
DOI: 10.1039/C3CC42069H
Chem. Commun., 2013,49, 5565-5567

  •   Request permissions

    A ratiometric naphthalimide sensor for live cell imaging of copper(I)

    C. Satriano, G. T. Sfrazzetto, M. E. Amato, F. P. Ballistreri, A. Copani, M. L. Giuffrida, G. Grasso, A. Pappalardo, E. Rizzarelli, G. A. Tomaselli and R. M. Toscano, Chem. Commun., 2013, 49, 5565
    DOI: 10.1039/C3CC42069H

Search articles by author

Spotlight

Advertisements