Issue 41, 2013
From the journal:

Chemical Communications

Pd-catalyzed diastereoselective allylation of aldehydes with 3-bromomethyl-5H-furan-2-one: stereoselective synthesis of β-(hydroxymethylaryl/alkyl)-α-methylene-γ-butyrolactones with a syn configuration†

Fuhai Zhang,a   Yanxin Yang,a   Longguan Xiea  and  Xiaohua Xu*a  

* Corresponding authors

a State Key Laboratory of Elemento-Organic Chemistry, Nankai University, Tianjin 300071, China
E-mail: xiaohuaxu@nankai.edu.cn
Fax: +86 22 23504284

Abstract

An efficient and diastereoselective Pd-catalyzed method of allylation of aldehydes with 3-bromomethyl-5H-furan-2-one is described. The proposed method allows the synthesis of β-(hydroxymethylaryl/alkyl)-α-methylene-γ-butyrolactones with a syn relative configuration for the first time.

Graphical abstract: Pd-catalyzed diastereoselective allylation of aldehydes with 3-bromomethyl-5H-furan-2-one: stereoselective synthesis of β-(hydroxymethylaryl/alkyl)-α-methylene-γ-butyrolactones with a syn configuration

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C3CC41501E
Article type
Communication
Submitted
28 Feb 2013
Accepted
03 Apr 2013
First published
05 Apr 2013

Chem. Commun., 2013,49, 4697-4699

Permissions

Request permissions

Pd-catalyzed diastereoselective allylation of aldehydes with 3-bromomethyl-5H-furan-2-one: stereoselective synthesis of β-(hydroxymethylaryl/alkyl)-α-methylene-γ-butyrolactones with a syn configuration

F. Zhang, Y. Yang, L. Xie and X. Xu, Chem. Commun., 2013, 49, 4697 DOI: 10.1039/C3CC41501E

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements