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Issue 31, 2013
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Reactions of organolithiums with dialkyl oxalates. A flow microreactor approach to synthesis of functionalized α-keto esters

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Abstract

Reactions of functionalized aryllithiums with dialkyl oxalates were achieved using a flow microreactor to obtain α-keto esters with high selectivity by virtue of fast 1 : 1 micromixing.

Graphical abstract: Reactions of organolithiums with dialkyl oxalates. A flow microreactor approach to synthesis of functionalized α-keto esters

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Article information


Submitted
17 Jan 2013
Accepted
28 Feb 2013
First published
13 Mar 2013

Chem. Commun., 2013,49, 3242-3244
Article type
Communication

Reactions of organolithiums with dialkyl oxalates. A flow microreactor approach to synthesis of functionalized α-keto esters

A. Nagaki, D. Ichinari and J. Yoshida, Chem. Commun., 2013, 49, 3242
DOI: 10.1039/C3CC40392K

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