Issue 22, 2013
From the journal:

Chemical Communications

Efficient quenching of electrochemiluminescence from K-doped graphene–CdS:Eu NCs by G-quadruplex–hemin and target recycling-assisted amplification for ultrasensitive DNA biosensing†

Hong Zhou,a   Yan-Yan Zhang,a   Jing Liu,a   Jing-Juan Xu*a  and  Hong-Yuan Chena  

* Corresponding authors

a State Key Laboratory of Analytical Chemistry for Life Science, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210093, China
E-mail: xujj@nju.edu.cn
Fax: +86-25-83597294
Tel: +86-25-83597294

Abstract

Based on the K-doped graphene–CdS:Eu NC composites and the nicking endonuclease (NEase) assisted strand-scission cycle, we have developed an ultrasensitive and selective electrochemiluminescence (ECL) DNA biosensor using the G-quadruplex–hemin-based DNAzyme which acts as an electrocatalyst for the reduction of H2O2, the coreactant of CdS:Eu NCs ECL.

Graphical abstract: Efficient quenching of electrochemiluminescence from K-doped graphene–CdS:Eu NCs by G-quadruplex–hemin and target recycling-assisted amplification for ultrasensitive DNA biosensing

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Article information

DOI
https://doi.org/10.1039/C3CC38990A
Article type
Communication
Submitted
17 Dec 2012
Accepted
01 Feb 2013
First published
01 Feb 2013

Chem. Commun., 2013,49, 2246-2248

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Efficient quenching of electrochemiluminescence from K-doped graphene–CdS:Eu NCs by G-quadruplex–hemin and target recycling-assisted amplification for ultrasensitive DNA biosensing

H. Zhou, Y. Zhang, J. Liu, J. Xu and H. Chen, Chem. Commun., 2013, 49, 2246 DOI: 10.1039/C3CC38990A

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