Issue 29, 2013
From the journal:

Chemical Communications

Detection of carbohydrates on the surface of cancer and normal cells by topography and recognition imaging†

Weidong Zhao,ab   Shuheng Liu,a   Mingjun Cai,a   Haijiao Xu,a   Junguang Jianga  and  Hongda Wang*ab  

* Corresponding authors

a State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, Jilin 130022, P.R. China
E-mail: hdwang@ciac.jl.cn
Fax: +86 0431 85262804
Tel: +86 0431 85262453

b University of Chinese Academy of Sciences, Beijing 100049, P.R.China

Abstract

Galactose was detected and localized on the surface of cancer and normal cells by topography and recognition imaging at the single molecular level. There are more galactoses on cancer cells than on normal cells. The stability of galactose–lectin on cancer cells is much lower than that on normal cells.

Graphical abstract: Detection of carbohydrates on the surface of cancer and normal cells by topography and recognition imaging

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Article information

DOI
https://doi.org/10.1039/C3CC38885A
Article type
Communication
Submitted
12 Dec 2012
Accepted
22 Jan 2013
First published
12 Feb 2013

Chem. Commun., 2013,49, 2980-2982

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Detection of carbohydrates on the surface of cancer and normal cells by topography and recognition imaging

W. Zhao, S. Liu, M. Cai, H. Xu, J. Jiang and H. Wang, Chem. Commun., 2013, 49, 2980 DOI: 10.1039/C3CC38885A

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