Enzyme-free strip biosensor for amplified detection of Pb2+ based on a catalytic DNA circuit

Junhua Chen; Xuemeng Zhou; Lingwen Zeng

doi:10.1039/C2CC37598B

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Enzyme-free strip biosensor for amplified detection of Pb²⁺ based on a catalytic DNA circuit†

Junhua Chen,^a Xuemeng Zhou^a and Lingwen Zeng*^a

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* Corresponding authors

^a Key Laboratory of Regenerative Biology, South China Institute for Stem Cell Biology and Regenerative Medicine, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou 510530, China
E-mail: zeng6@yahoo.com
Fax: +86 20 32015245
Tel: +86 20 32015312

Abstract

A simple and enzyme-free strip biosensor for the amplified detection of Pb²⁺ has been constructed based on a catalytic DNA circuit. This assay is ultrasensitive, enabling the visual detection of Pb²⁺ concentrations as low as 10 pM without instrumentation.

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Article information

DOI: https://doi.org/10.1039/C2CC37598B
Article type: Communication
Submitted: 18 Oct 2012
Accepted: 10 Dec 2012
First published: 12 Dec 2012

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Chem. Commun., 2013,49, 984-986

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Enzyme-free strip biosensor for amplified detection of Pb²⁺ based on a catalytic DNA circuit

J. Chen, X. Zhou and L. Zeng, Chem. Commun., 2013, 49, 984 DOI: 10.1039/C2CC37598B

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