Issue 9, 2013
From the journal:

Chemical Communications

Quantum dot-DNA origami binding: a single particle, 3D, real-time tracking study†

Kan Du,‡ab   Seung Hyeon Ko,‡ab   Gregg M. Gallatin,a   Heayoung P. Yoon,ab   J. Alexander Liddle*a  and  Andrew J. Berglund*a  

* Corresponding authors

a Center for Nanoscale Science and Technology, National Institute of Standards and Technology, Gaithersburg, MD, USA
E-mail: liddle@nist.gov, ajberglund@gmail.com
Fax: +1 301-975-5314
Tel: +1 301-975-6050

b Maryland Nanocenter, University of Maryland, College Park, MD, USA

Abstract

The binding process of quantum dots and DNA origami was monitored using a 3D, real-time, single-particle tracking system. Single-molecule binding events were directly observed and precise measurements of the diffusion coefficient and second-order photon correlation function, g2(τ), were combined to distinguish free quantum dots from different conjugates of nQdot-origami.

Graphical abstract: Quantum dot-DNA origami binding: a single particle, 3D, real-time tracking study

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Article information

DOI
https://doi.org/10.1039/C2CC37517F
Article type
Communication
Submitted
15 Oct 2012
Accepted
10 Dec 2012
First published
12 Dec 2012

Chem. Commun., 2013,49, 907-909

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Quantum dot-DNA origami binding: a single particle, 3D, real-time tracking study

K. Du, S. H. Ko, G. M. Gallatin, H. P. Yoon, J. Alexander Liddle and A. J. Berglund, Chem. Commun., 2013, 49, 907 DOI: 10.1039/C2CC37517F

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