Issue 39, 2013
From the journal:

Chemical Communications

Rapid synthesis of oligomannosides with orthogonally protected monosaccharides†‡

Sue-Ming Chang,ab   Zhijay Tu,b   Hau-Ming Jan,ab   Jia-Fu Panb  and  Chun-Hung Lin*ab  

* Corresponding authors

a Institute of Biochemical Sciences, National Taiwan University, Taipei 10617, Taiwan

b Institute of Biological Chemistry and the Genomics Research Center, Academia Sinica, No. 128, Academia Road Section 2, Taipei 11529, Nan-Kang, Taiwan
E-mail: chunhung@gate.sinica.edu.tw
Fax: +886-2-26514705

Abstract

We developed a facile synthesis to yield orthogonally protected mannose building blocks with high overall yields. The protection/glycosylation steps can be carried out in a successive manner without purification of intermediate products. This developed synthesis led to formation of linear/branched tri-, penta- and heptasaccharides.

Graphical abstract: Rapid synthesis of oligomannosides with orthogonally protected monosaccharides

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Article information

DOI
https://doi.org/10.1039/C2CC37099A
Article type
Communication
Submitted
29 Sep 2012
Accepted
23 Oct 2012
First published
23 Oct 2012

Chem. Commun., 2013,49, 4265-4267

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Rapid synthesis of oligomannosides with orthogonally protected monosaccharides

S. Chang, Z. Tu, H. Jan, J. Pan and C. Lin, Chem. Commun., 2013, 49, 4265 DOI: 10.1039/C2CC37099A

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