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Issue 4, 2013
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A fluorescent probe for rapid detection of thiols and imaging of thiols reducing repair and H2O2 oxidative stress cycles in living cells

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Abstract

A diselenide containing fluorescent probe based on a fluorescein scaffold for thiols was developed. The fluorescent probe exhibited rapid response, high selectivity and reversibility. Confocal fluorescence microscopy was used to visualize the redox changes mediated by thiols and reactive oxygen species in living HeLa cells.

Graphical abstract: A fluorescent probe for rapid detection of thiols and imaging of thiols reducing repair and H2O2 oxidative stress cycles in living cells

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Supplementary files

Article information


Submitted
20 Sep 2012
Accepted
30 Oct 2012
First published
31 Oct 2012

Chem. Commun., 2013,49, 391-393
Article type
Communication

A fluorescent probe for rapid detection of thiols and imaging of thiols reducing repair and H2O2 oxidative stress cycles in living cells

Z. Lou, P. Li, X. Sun, S. Yang, B. Wang and K. Han, Chem. Commun., 2013, 49, 391
DOI: 10.1039/C2CC36839K

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