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Issue 76, 2012

Copper-catalyzed conversion of aryl and heteroaryl bromides into the corresponding chlorides

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Abstract

An efficient method for the synthesis of aryl and heteroaryl chlorides is described. The reactions of aryl and heteroaryl bromides with tetramethylammonium chloride proceeded smoothly in the presence of a copper catalyst under mild reaction conditions to produce the corresponding chlorides in satisfactory to excellent yields.

Graphical abstract: Copper-catalyzed conversion of aryl and heteroaryl bromides into the corresponding chlorides

Supplementary files

Article information


Submitted
11 Jul 2012
Accepted
02 Aug 2012
First published
02 Aug 2012

Chem. Commun., 2012,48, 9468-9470
Article type
Communication

Copper-catalyzed conversion of aryl and heteroaryl bromides into the corresponding chlorides

X. Feng, Y. Qu, Y. Han, X. Yu, M. Bao and Y. Yamamoto, Chem. Commun., 2012, 48, 9468 DOI: 10.1039/C2CC34944B

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