Issue 95, 2012
From the journal:

Chemical Communications

Recent trends in Cys- and Ser/Thr-based synthetic strategies for the elaboration of peptide constructs

Jean-Christophe M. Monbaliu†ab  and  Alan R. Katritzky*ac  

* Corresponding authors

a Center for Heterocyclic Compounds, Department of Chemistry, University of Florida, Gainesville, USA
E-mail: katritzky@chem.ufl.edu

b Department of Sustainable Organic Chemistry and Technology, Faculty of Bioscience Engineering, Ghent University, B-9000 Ghent, Belgium

c Chemistry Department, King Abdulaziz University, 21589 Saudi Arabia, Jeddah

Abstract

Recent conceptual advances in the chemical synthesis of peptide constructs are described, encompassing native chemical ligation (i.e. the chemoselective covalent condensation of unprotected peptide segments) and O-, S-acyl isopeptide strategies (i.e. internal O,S-to-N acyl transfer within peptides).

Graphical abstract: Recent trends in Cys- and Ser/Thr-based synthetic strategies for the elaboration of peptide constructs

About
Cited by
Related
Download options Please wait...

Article information

DOI
https://doi.org/10.1039/C2CC34434C
Article type
Feature Article
Submitted
20 Jun 2012
Accepted
12 Sep 2012
First published
13 Sep 2012

Chem. Commun., 2012,48, 11601-11622

Permissions

Request permissions

Recent trends in Cys- and Ser/Thr-based synthetic strategies for the elaboration of peptide constructs

J. M. Monbaliu and A. R. Katritzky, Chem. Commun., 2012, 48, 11601 DOI: 10.1039/C2CC34434C

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements