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Issue 75, 2012
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Poly[2-(methacryloyloxy)ethylphosphorylcholine]-coated iron oxide nanoparticles: synthesis, colloidal stability and evaluation for stem cell labelling†

Anita K. Peacock,a   Solène I. Cauët,a   Arthur Taylor,b   Patricia Murray,b   Steve R. Williams,c   Jonathan V. M. Weaver,‡d   Dave J. Adamsa  and  Matthew J. Rosseinsky*a  
Author affiliations

* Corresponding authors

a Department of Chemistry, University of Liverpool, Liverpool, UK

b Institute of Translational Medicine, University of Liverpool, UK

c Imaging Science and Biomedical Engineering, University of Manchester, Manchester, UK

d Department of Materials and Department of Bioengineering, Imperial College London, London, UK
E-mail: m.j.rosseinsky@liv.ac.uk
Fax: +44 (0)151 794 3528
Tel: +44 (0)151 794 3499

Abstract

Poly[2-(methacryloyloxy)ethylphosphorylcholine]-coated SPIONs were prepared through ATRP and amidation coupling reactions. The coated SPIONs exhibited high stability and re-dispersability in phosphate buffered saline and uptake in a stem cell line, with high T2 relaxivity.

Graphical abstract: Poly[2-(methacryloyloxy)ethylphosphorylcholine]-coated iron oxide nanoparticles: synthesis, colloidal stability and evaluation for stem cell labelling

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Article information

https://doi.org/10.1039/C2CC34420C
Submitted
20 Jun 2012
Accepted
25 Jul 2012
First published
26 Jul 2012
Chem. Commun., 2012,48, 9373-9375
Article type
Communication
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Poly[2-(methacryloyloxy)ethylphosphorylcholine]-coated iron oxide nanoparticles: synthesis, colloidal stability and evaluation for stem cell labelling

A. K. Peacock, S. I. Cauët, A. Taylor, P. Murray, S. R. Williams, J. V. M. Weaver, D. J. Adams and M. J. Rosseinsky, Chem. Commun., 2012, 48, 9373
DOI: 10.1039/C2CC34420C

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