Issue 69, 2012

Expeditious synthesis of saponin P57, an appetite suppressant from Hoodia plants

Abstract

Pregnane glycoside P57, the appetite suppressant component from Hoodia, was synthesized expeditiously, featuring preparation of the aglycone Hoodigogenin A from digoxin and assembly of the deoxytrisaccharide with glycosyl o-alkynylbenzoates as donors.

Graphical abstract: Expeditious synthesis of saponin P57, an appetite suppressant from Hoodia plants

Supplementary files

Article information

Article type
Communication
Submitted
20 Jun 2012
Accepted
06 Jul 2012
First published
06 Jul 2012

Chem. Commun., 2012,48, 8679-8681

Expeditious synthesis of saponin P57, an appetite suppressant from Hoodia plants

J. Zhang, H. Shi, Y. Ma and B. Yu, Chem. Commun., 2012, 48, 8679 DOI: 10.1039/C2CC34404A

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