Jump to main content
Jump to site search

Issue 68, 2012
Previous Article Next Article

Live cell imaging of lysosomal pH changes with pH responsive ratiometric lanthanide probes

Author affiliations

Abstract

Europium and terbium complexes of two structurally related ligands have been evaluated as optical probes to monitor changes in lysosomal pH; calibration using ionophores and fluorescent probes allows monitoring of the time dependence of lysosomal pH change, examining the green/red intensity ratio from internalised Tb–Eu complexes.

Graphical abstract: Live cell imaging of lysosomal pH changes with pH responsive ratiometric lanthanide probes

Back to tab navigation

Supplementary files

Publication details

The article was received on 14 Jun 2012, accepted on 10 Jul 2012 and first published on 11 Jul 2012


Article type: Communication
DOI: 10.1039/C2CC34267G
Chem. Commun., 2012,48, 8520-8522

  •   Request permissions

    Live cell imaging of lysosomal pH changes with pH responsive ratiometric lanthanide probes

    D. G. Smith, B. K. McMahon, R. Pal and D. Parker, Chem. Commun., 2012, 48, 8520
    DOI: 10.1039/C2CC34267G

Search articles by author

Spotlight

Advertisements