Issue 72, 2012
From the journal:

Chemical Communications

Discrimination of colon cancer stem cells using noncanonical amino acid†

Xinrui Duan,a   Honglin Li,a   Hexin Chenb  and  Qian Wang*a  

* Corresponding authors

a Department of Chemistry and Biochemistry & Nanocenter, University of South Carolina, Columbia, USA
E-mail: wang263@mailbox.sc.edu

b Department of Biology, University of South Carolina, Columbia, USA

Abstract

Cancer stem cells (CSCs) may be responsible for tumor recurrence. Metabolic labelling of newly synthesized proteins with non-canonical amino acids allows us to discriminate CSCs in mixed populations due to the quiescent nature of these cells.

Graphical abstract: Discrimination of colon cancer stem cells using noncanonical amino acid

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Article information

DOI
https://doi.org/10.1039/C2CC33776B
Article type
Communication
Submitted
25 May 2012
Accepted
20 Jul 2012
First published
20 Jul 2012

Chem. Commun., 2012,48, 9035-9037

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Discrimination of colon cancer stem cells using noncanonical amino acid

X. Duan, H. Li, H. Chen and Q. Wang, Chem. Commun., 2012, 48, 9035 DOI: 10.1039/C2CC33776B

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